Product Description
Casein Kinase IIα (T251) polyclonal antibody is available at gentaur for next week delivery
Background: Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIα, γ, e and δ, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The a catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Casein Kinase IIα (T251) polyclonal antibody detects endogenous levels of Casein kinase II subunit alpha protein.
W4BiowMW: ~ 45 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to amino acids 220-270 of Human Casein Kinase IIα.Alternative Name:
CK II; CKII alpha; 1457; CSNK2A1; CK2A1; CKII; CKII alpha; Casein kinase II subunit alpha; Casein Kinase IIα; CKIIα; CK-IIα; CKII-α; CK IIα; CKII α; CKIIα;Western blot analysis: Western blot analysis of extracts of various cell lines, using CSNK2A1 antibody at 1:1000 dilution. Lysates/proteins: 40ug per lane. Exposure time: 1s.
Immunohistochemistry: Immunohistochemistry - CSNK2A1 Rabbit pAb
Immunofluorescence analysis: Immunohistochemistry - CSNK2A1 Rabbit pAb
Host: Rabbit
Swiss-Prot: P68400
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