Product Description
CaMK2 alpha/beta/delta (Phospho-T305) polyclonal antibody is available at gentaur for next week delivery
Background: The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated α, β, γ and δ, which may or may not be co-expressed in the same tissue type. CaMKIIα is autophosphorylated on Thr 286 upon the binding of the Ca2+/CaM complex to the autoinhibitory domain of CaMKII. This process is called Ca2+/CaM trapping, which is thought to be involved in the synaptic encoding of information.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CaMK2 alpha/beta/delta (Phospho-T305) polyclonal antibody detects endogenous levels of CaMK2 alpha/beta/delta protein only when phosphorylated at Thr305.
W4BiowMW: ~ 50 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic phosphopeptide derived from human CaMK2 alpha/beta/delta around the phosphorylation site of Threonine 305.Alternative Name:
Calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2A; CAMKA; KIAA0968; CaMK2-a; CaMK2a; CaMK-2a; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II subunit delta; CaMK-II subunit delta; CAMK2D; CAMKD; CaMK2-δ; CaMK2δ; CaMK-2δ;Western blot analysis: Western blot (WB) analysis of CaMK2 alpha/beta/delta (Phospho-T305) polyclonal antibody at 1:500 dilution LaneA:HEK293T whole cell lysate LaneB:U-87MG whole cell lysate LaneC:A549 whole cell lysate LaneD:The Brain tissue lysate of Rat
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q9UQM7/Q13554/Q13557
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