Product Description
BRD3 (F645) polyclonal antibody is available at gentaur for next week delivery
Background: The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomaincontaining proteins are ubiquitously expressed.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: BRD3 (F645) polyclonal antibody detects endogenous levels of BRD3 protein.
W4BiowMW: ~72 kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to amino acids 614-667 of Human BRD3.Alternative Name:
Bromodomain-containing protein 3; RING3-like protein; BRD3; KIAA0043; RING3LWestern blot analysis: Western blot (WB) analysis of BRD3 pAb at 1:1000 dilution Lane1:SGC7901 whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(40ug) Lane3:Jurkat whole cell lysate(40ug)
Immunohistochemistry: Immunohistochemistry (IHC) analyzes of BRD3 (F645) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q15059
"
