Product Description
Bcl-7a (N62) polyclonal antibody is available at gentaur for next week delivery
Background: Bcl-7a (B-cell CLL/lymphoma 7 protein family member A) is a 210 amino acid protein that belongs to the Bcl-7 family. Chromosomal aberrations involving a disruption of the amino-terminus of Bcl-7a may be a cause of B-cell nonHodgkin lymphoma (BNHL). Bcl-7b and Bcl-7c proteins share 90% identity with the N-terminal 51 amino acids of Bcl-7a, suggesting that the three genes are members of an evolutionarily conserved gene family. Bcl-7 gene family may be involved in early development. The Bcl-7a protein interacts with a novel human Polycomb ring finger gene and exists as two alternatively spliced isoforms. Bcl-7a may play a role in GC reaction and/or B-cell lymphomagenesis. The Bcl-7a gene maps to human chromosome 12q24.31. Chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Bcl-7a (N62) polyclonal antibody detects endogenous levels of Bcl-7a protein.
W4BiowMW: ~ 26 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to amino acids 30-84 of Human Bcl-7a.Alternative Name:
B cell CLL/lymphoma 7; B cell CLL/lymphoma 7 protein family member A; B cell CLL/lymphoma 7A; B-cell CLL/lymphoma 7 protein family member A; BCL 7; BCL7; bcl7a; BCL7AWestern blot analysis: Western blot (WB) analysis of BCL7A pAb at 1:500 dilution Lane1:The Fallopian tube tissue lysate of Rat(40ug) Lane2:The Embryo tissue lysate of Mouse(40ug) Lane3:PC12 whole cell lysate(40ug) Lane4:CT-26 whole cell lysate (40ug) Lane5:PC3 whole cell lysate(40ug) Lane6:A2780 whole cell lysate(40ug) Lane7:LOVO whole cell lysate(40ug)
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q4VC05
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