ATP6AP2 polyclonal antibody

Product Description

ATP6AP2 polyclonal antibody is available at gentaur for next week delivery

Background: The Renin Receptor, also known as ATP6AP2 (ATPase H+-transporting lysosomal accessory protein 2), ATP6IP2 (ATPase H+-transporting lysosomal-interacting protein 2), CAPER or M8-9, is an ATPase-associated protein that functions as a Renin and prorenin cellular receptor. Expressed in the brain, heart, liver, kidney, placenta and pancreas, the Renin Receptor functions to activate ERK 1 and ERK 2, thereby mediating Renin-dependent cellular responses. The Renin Receptor has a subunit that associates with the transmembrane domain of V-type ATPases and interacts with Renin. These interactions increase the catalytic activity of Renin in the Renin-Angiotensin system (RAS), thus upregulating the conversion of angiotensinogen to Angiotensin.

Applications:  WB IF

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  ATP6AP2 polyclonal antibody detects endogenous levels of ATP6AP2 protein.

W4BiowMW:  ~ 48kDa

Reactivity: Human,Mouse,Rat

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Recombinant full length Human ATP6AP2.

Alternative Name:

ATPase H(+)-transporting lysosomal accessory protein 2; ATPase H(+)-transporting lysosomal-interacting protein 2; ER-localized type I transmembrane adaptor; Embryonic liver differentiation factor 10 N14F; Renin/prorenin receptor; Vacuolar ATP synthase membrane sector-associated protein M8-9; ATP6M8-9; V-ATPase M8.9 subunit; ATP6AP2; ATP6IP2; CAPER; ELDF10; HT028; MSTP009; PSEC0072

Western blot analysis:  Immunofluorescence analysis of HeLa cell using ATP6AP2 antibody. Blue: DAPI for nuclear staining.

Immunohistochemistry: Western blot analysis of extracts of various cell lines, using ATP6AP2 antibody.

Immunofluorescence analysis:

Host:  Rabbit

Swiss-Prot: O75787

 

 

 

 

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