Product Description
ATP1A2 polyclonal antibody is available at gentaur for next week delivery
Background: The ubiquitously expressed sodium/potassium-ATPase (Na+/K+-ATPase) exists as an oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, Na+/K+-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, α, β and γ, comprise the Na+/K+-ATPase oligomer. The α subunit contains the binding sites for ATP and the cations; the glycosylated β subunit ensures correct folding and membrane insertion of the α subunits. The small γ subunit co-localizes with the α subunit in nephron segments, where it increases the affinity of Na+/K+-ATPase for ATP. The β subunit, but not the γ subunit, is essential for normal activity of Na+/K+-ATPase.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ATP1A2 polyclonal antibody detects endogenous levels of ATP1A2 protein.
W4BiowMW: ~ 95kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human ATP1A2 .Alternative Name:
Sodium/potassium-transporting ATPase subunit alpha-2;Na(+)/K(+) ATPase alpha-2 subunit;Sodium pump subunit alpha-2;ATP1A2;KIAA0778;Western blot analysis: Western blot (WB) analysis of ATP1A2 polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:H1792 whole cell lysate(40ug) Lane3:Panc1 whole cell lysate(40ug) Lane4:Aml-12 whole cell lysate(40ug)
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P50993
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