ATF6B (S425) polyclonal antibody

Product Description

ATF6B (S425) polyclonal antibody is available at gentaur for next week delivery

Background: ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6β homodimer or an ATF-6α/β heterodimer. Binding of the ATF-6β homodimer or ATF-6α/β heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription.

Applications:  WB

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  ATF6B (S425) polyclonal antibody detects endogenous levels of ATF6B protein.

W4BiowMW:  ~ 90 kDa

Reactivity: Human,Mouse,Rat

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Synthetic peptide, corresponding to amino acids 390-442 of Human ATF6B.

Alternative Name:

Cyclic AMP-dependent transcription factor ATF-6 beta; cAMP-dependent transcription factor ATF-6 beta; Activating transcription factor 6 beta; ATF6-beta; Protein G13; cAMP response element-binding protein-related protein; Creb-rp; cAMP-responsive element-binding protein-like 1; Processed cyclic AMP-dependent transcription factor ATF-6 beta; ATF6B; CREBL1; G13; ATF-6β; ATF6β

Western blot analysis:  Western blot (WB) analysis of ATF6B pAb at 1:500 dilution Lane1:The Embryo tissue lysate of Mouse(40ug) Lane2:C6 whole cell lysate(40ug) Lane3:CT-26 whole cell lysate(40ug) Lane4:HEK293T whole cell lysate (40ug) Lane5:DLD whole cell lysate(40ug) Lane6:A2780 whole cell lysate(40ug)

Immunohistochemistry:

Immunofluorescence analysis:

Host:  Rabbit

Swiss-Prot: Q99941

 

 

 

 

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