Product Description
ARRB1 polyclonal antibody is available at gentaur for next week delivery
Background: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ARRB1 polyclonal antibody detects endogenous levels of ARRB1 protein.
W4BiowMW: ~ 56 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 169-418 of human ARRB1Alternative Name:
ARRB1; ARB1; ARR1Western blot analysis: Western blot analysis of extracts of various cell lines, using ARRB1 antibody at 1:1000 dilution. Lysates/proteins: 25ug per lane.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded rat heart using ARRB1 antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis: Immunohistochemistry of paraffin-embedded mouse spleen using ARRB1 antibody at dilution of 1:100 (40x lens).
Host: Rabbit
Swiss-Prot: P49407
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