Product Description
AR polyclonal antibody is available at gentaur for next week delivery
Background: Androgens exhibit a wide range of effects on the development, maintenance and regulation of male phenotype and reproductive physiology in males. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind active testosterone (T) and dihydrotestosterone (DHT). The rates of association and dissociation of T are about 3 times more rapid than those of DHT. This difference in binding kinetics may account for the different physiological effects of T and DHT. Androgen binding results in an at least 6-fold increase in androgen receptor stability.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: AR polyclonal antibody detects endogenous levels of AR protein.
W4BiowMW: ~ 110 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human AR.Alternative Name:
Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AR; DHTR; NR3C4Western blot analysis: Western blot analysis of extracts of various cell lines, using AR antibody.
Immunohistochemistry:
Immunofluorescence analysis: Immunofluorescence analysis of A549 cells, using AR polyclonal antibody
Host: Rabbit
Swiss-Prot: P10275
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