Product Description
Anti-SIRT1 Polyclonal Antibody is available at Gentaur for next week delivery
Description: The original biosimilar is a chimeric monoclonal antibody against CD4 which acts as an immunomodulator and has been investigated for treatment of rheumatoid arthritis. CD4 acts as a coreceptor with the T-cell receptor on T lymphocytes to recognize antigens displayed by antigen presenting cells in the context of a class II MHC molecule. CD4 is also a primary viral entry point for the human immunodeficiency virus. The CD4 antigen is expressed by many cell types in addition to T lymphocytes, and is responsible for immune responses against pathogens and other stimuli.
Application And Usages:
Anti-SIRT1 Polyclonal Antibody is available at Gentaur for next week delivery
Description: Sirtuin 1 (SIRT1) is an NAD-dependent protein deacetylase that links transcriptional regulation directly to myriad cellular functions such as cell cycle control, metabolism, apoptosis, and autophagy. SIRT1 can modulate chromatin function through histone deacetylation which leads to transcriptional repression of target genes. SIRT1 can also directly deacetylate transcription factors, which positively and negatively regulates target gene expression depending on the affected transcription factor. Among the proteins affected by SIRT1 are ARNTL, PER2, and CRY1, demonstrating a key role for SIRT1 in the regulation of circadian rhythm.
Application And Usages: Western Blotting Immunofluorescence (IF) Immunohistochemistry (IHC)
Target Alternative Name: Sirtuin 1; SIR2L1; SIR2-Like Protein 1; Sirtuin Type 1; HSIRT1; HSIR2; SIR2;
Tag Line: Coordinates cellular functions including cell cycle regulation, metabolism, apoptosis, and autophagy
Antibody Target: Human SIRT1
Form: Rabbit polyclonal
Formulation: In 0.42% potassium phosphate, 0.87% NaCl, pH 7.3, w/30% glycerol and 0.01% sodium azide
Purification: Immunogen affinity chromatography
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Immunogen Sequence: KLH-conjugated synthetic peptide of human SIRT1
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Host: Rabbit
Target Alternative Name: Sirtuin 1; SIR2L1; SIR2-Like Protein 1; Sirtuin Type 1; HSIRT1; HSIR2; SIR2
Tag Line: Sirtuin 1; SIR2L1; SIR2-Like Protein 1; Sirtuin Type 1; HSIRT1; HSIR2; SIR2
Antibody Target: Human SIRT1
Form: Rabbit polyclonal
Formulation: In 0.42% potassium phosphate, 0.87% NaCl, pH 7.3, w/30% glycerol and 0.01% sodium azide
Purification: Immunogen affinity chromatography
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Immunogen Sequence: KLH-conjugated synthetic peptide of human SIRT1
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Host: Rabbit
