Product Description
Anti-MTNR1B Polyclonal Antibody is available at Gentaur for next week delivery
Description: Sirtuin 1 (SIRT1) is an NAD-dependent protein deacetylase that links transcriptional regulation directly to myriad cellular functions such as cell cycle control, metabolism, apoptosis, and autophagy. SIRT1 can modulate chromatin function through histone deacetylation which leads to transcriptional repression of target genes. SIRT1 can also directly deacetylate transcription factors, which positively and negatively regulates target gene expression depending on the affected transcription factor. Among the proteins affected by SIRT1 are ARNTL, PER2, and CRY1, demonstrating a key role for SIRT1 in the regulation of circadian rhythm.
Application And Usages:
Anti-MTNR1B Polyclonal Antibody is available at Gentaur for next week delivery
Description: The Melatonin Receptor 1B (MTNR1B) is one of two high affinity forms of receptor that binds melatonin, the primary hormone product of the pineal gland. MTNR1B is found primarily in the retina and brain, especially in the suprachiasmatic nucleus. MTNR1B is thought to mediate the reproductive and circadian actions of melatonin, as well as light-dependent functions in the retina.
Application And Usages: Western Blotting
Target Alternative Name: Melatonin Receptor 1B; Mel1b Receptor; MEL1B; MEL-1B-R; FGQTL2; MT2;
Tag Line: Likely to mediate reproductive and circadian actions of melatonin
Antibody Target: Human MTNR1B
Form: Rabbit polyclonal
Formulation: In 0.42% potassium phosphate, 0.87% NaCl, pH 7.3, w/30% glycerol and 0.01% sodium azide
Purification: Immunogen affinity chromatography
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Immunogen Sequence: KLH conjugated synthetic peptide of Human MTNR1B
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Host: Rabbit
Target Alternative Name: Melatonin Receptor 1B; Mel1b Receptor; MEL1B; MEL-1B-R; FGQTL2; MT2
Tag Line: Melatonin Receptor 1B; Mel1b Receptor; MEL1B; MEL-1B-R; FGQTL2; MT2
Antibody Target: Human MTNR1B
Form: Rabbit polyclonal
Formulation: In 0.42% potassium phosphate, 0.87% NaCl, pH 7.3, w/30% glycerol and 0.01% sodium azide
Purification: Immunogen affinity chromatography
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Immunogen Sequence: KLH conjugated synthetic peptide of Human MTNR1B
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Host: Rabbit
