Product Description
AMD1 polyclonal antibody is available at gentaur for next week delivery
Background: AdoMetDC (adenosylmethionine decarboxylase 1), also known as S-adenosylmethionine decarboxylase proenzyme (SAMDC) or AMD1, is a 334 amino acid protein which is an important intermediate enzyme in polyamine biosynthesis pathways. Using a pyruvoyl group as a cofactor, AdoMetDC catalyzes the conversion of S-adenosyl-L-methionine to (5-deoxy-5-adenosyl)(3-aminopropyl)-methylsulfonium salt and carbon dioxide. AdoMetDC is synthesized as an inactive proenzyme that undergoes self-maturation to form two non-identical subunits designated α and β. Active AdoMetDC forms a heterotetramer of two α chains and two β chains. Both AdoMetDC proenzyme processing and mature AdoMetDC catalytic activity are stimulated by putrescine, while catalytic activity is inhibited by iodoacetic acid.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: AMD1 polyclonal antibody detects endogenous levels of AMD1 protein.
W4BiowMW: ~ 38 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
A synthetic peptide corresponding to residues in Human AMD1.Alternative Name:
S-adenosylmethionine decarboxylase proenzyme; AdoMetDC; SAMDC; S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain; AMDWestern blot analysis: Western blot (WB) analysis of AMD1 pAb at 1:500 dilution Lane1:AML-12 whole cell lysate(40ug) Lane2:HCT116 whole cell lysate(40ug) Lane3:L02 whole cell lysate(40ug) Lane4:HepG2 whole cell lysate(40ug) Lane5:A549 whole cell lysate(40ug)
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P17707
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