Product Description
ADAMTS5 polyclonal antibody is available at gentaur for next week delivery
Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ADAMTS5 polyclonal antibody detects endogenous levels of ADAMTS5 protein.
W4BiowMW: ~ 73 kDa
Reactivity: Human, Mouse, Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 731-930 of human ADAMTS5.Alternative Name:
ADAMTS5; ADAM-TS 11; ADAM-TS 5; ADAM-TS5; ADAMTS-11; ADAMTS-5; ADAMTS11; ADMP-2; ADAM-TS11Western blot analysis: Western blot (WB) analysis of ADAMTS5 polyclonal antibody at 1:1000 dilution. Lysates/proteins: 25ug per lane.
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q9UNA0
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