Product Description
ACTR-IIA polyclonal antibody is available at gentaur for next week delivery
Background: Members of the transforming growth factor β superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (ACVR2A) or ACTR-IIB (ACVR2B). Both receptor types are highly expressed in brain. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation and morphogenesis in a dose dependent manner.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ACTR-IIA polyclonal antibody detects endogenous levels of ACTR-IIA protein.
W4BiowMW: ~ 57 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human ACTR-IIA.Alternative Name:
Activin receptor type-2A; EC=2.7.11.30; Activin receptor type IIA; ACTR-IIA; ACTRIIA; ACVR2A; ACVR2Western blot analysis: Western blot analysis of ACTR-IIA polyclonal antibody
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P27037
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