Anti-MOUSE CD41 Antibodies

Catalog#: RDI-MCD41-REG30 Price: $500.00/1pkg

Package Size: 0.5mg in 1ml (0.5mg/ml) 10mM phosphate buffer, pH7.2 with 150mM NaCl and 0.09% NaN3

Clone: MWREG30

Ig Isotype: Rat IgG1k

Purification: Purified from TCS by affinity chromatography

Reactivity: Reacts with mouse glycoprotein IIb, also called integrin alpha IIb chains (CD41), which associates with integrin B3 chain to form the gpIIb/IIIa (CD41/CD61) complex. CD41/CD61 is expressed on platelets and magakaryocytes and binds to fibrinogen, fibronectin, vWF and thrombospondin

USE: -flow cytometry

-immunoprecipitation

-histochemistry (acetone fixed frozen section, titrate from 10ug/ml)

-in vivo depletion of thrombocytes (using an azide free formulation)

-in vivo induction of pathology of early stages of endotoxic shock

-in vivo inhibition of platelet aggregation

ref:

-Cell 65:359-362 (1991)

-Blood 94:684-693 (1999)

Storage: Store at 4 Deg C

Precautions:For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. Sodium azide may form explosive compounds in presence of heavy metals or under acidic conditions. Flush drains with copious amounts of water to prevent buildup of explosive compounds.

also available:FITC labeled cat#RDI-MCD41-REG30FT $594.00/0.5mg