RDI Divison of researchd Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.
Alpha-1-Anti-Chymotrypsin Antibodies (see rabbit polyclonal and mouse monolconals below)
Rabbit anti-Alpha-1-anti-chymotrypsin
cat# RDI-A1ACTabr $281.00/1ml
Presentation: 1ml purified rabbit antibody fraction in 10mM PBS, pH 7.4, with 0.2% BSA and 15mM sodium azize
Immunogen: Purified human serum Alpha-1-Antichymotrypsin
Species Reactivity: Human. Does not react with cow, horse, goat, sheep, pig, mink, kangaroo, cat,dog, guinea pig, mouse, rat, chicken
Known Applications: Immunohistology (frozen & formalin/paraffin) (For staining of formalin-fixed, paraffin-embedded tissues, digest the sections with trypsin at 1mg/ml PBS, for 5 min at RT).
Positive Control: Monocytes and macrophages in colon, tonsil, or skin
Cellular Localization: Cytoplasmic
Working Dilutions: Immunohistology: 1:50-1:100 (30 minute at RT) The optimal dilution for a specific application under a given set of experimental conditions should be determined by the investigator.
Storage : Store vial at 2-8 DEG C.
Specificity : Recognizes a protein of 62kDa which is identified as Alpha-1-Antichymotrypsin (Alpha-1-ACT). This polyclonal antibody is highly specific to Alpha-1-ACT and shows no cross-reaction with other related proteins. Alpha 1-ACT is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT. A higher proportion of serum PSA is complexed to Alpha-1- ACT in prostate cancer than in benign prostate hyperplasia.