rev:  January 17, 2005

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  VIRAL ANTIGENS/Pure Proteins 

(for in vitro research use only)

RDI Division of Fitzgerald Industries Intl  offers a wide line of  antigens for use in histochemistry, ELISA, and further manufacturing use. Please inquire for other antigens or antibodies to use with these products. Please inquire for Bulk quantities-significant discounts available!


see below 4 forms
Varicella Zoster Viral Antigen (Natural Isolates)

cat#RDI-VZVSOL-AG   $312.00/1ml + $125/ml 2 or more $1562.00/10ml Bulk quotes on request

Viral Strain: ELLEN from ATCC, Propagated in HF Cells ,in 0.1 M Glycine, pH 9.5 +/- 0.2 ,approx 0.1 - 0.25 mg/ml (<10% Viral Protein) Store -70oC

Varicella-Zoster Virus antigen is prepared by glycine extraction of human fibroblasts infected with VZV, strain ELLEN (ATCC). The inactivated antigen is partially purified to reduce host cell components. This preparation yields high sensitivity and low background in the ELISA and other solid phase immunoassays.

Varicella-Zoster Virus (VZV) is the etiologic agent of two clinical diseases: varicella or "chickenpox" and zoster or "shingles." Varicella, a mild infection in normal children, represents a major problem in immunocompromised patients. It is the leading cause of death from an infectious agent in leukemic children who are in remission.  

The presence of serum antibody to VZV has been shown to correlate with immunity to varicella. Determination of immune status to varicella is important for hospital personnel in contact with immunocompromised patients. When the live attenuated VZV vaccine becomes licensed, it will be necessary to determine the immune status of patients to evaluate their eligibility to receive the vaccine.

For research Use Only For research Use Only


Recombinant Varicella Zoster Virus gE (VZV-gE)

Cat# RDI-VZV231-AG    $625.00/0.5mg   $1125/1mg   Bulk quotes on request

PRODUCT  DESCRIPTION: E.coli derived recombinant.

The protein contains the VZV gE immunodominant regions.

Varicella-zoster virus interacts with cell surface heparin suplfate proteoglycans during virus attachment. VZV-gE is a glycoprotein that plays an active or supportive role in VZV cell membrane fusion. VZV-gE was found to enhance the fusogenic protenial of VZV gB

PURIFICATION  METHOD: Purified by proprietary chromatographic technique.

PURITY: Protein is >95% pure as determined by 10% PAGE (coomassie staining).

PROTEIN CONC: 1mg/ml in 25mM Tris-Hcl pH 8.0, 1mM EDTA and 50% glycerol.

STORAGE: Protein is shipped at ambient temperature. Upon arrival, Store at -200C.

STABILITY: Five years frozen. One month in solution at room temperature.

SPECIFICITY: Immunoreactive with sera of VZV infected individuals.

APPLICATIONS: Antigen in ELISA and Western blots, excellent antigen for detection of VZV with minimal specificity problems.

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics.  It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


Recombinant Varicella Zoster Virus ORF9

Cat# RDI-VZV232-AG    $625.00/0.5mg   $1125/1mg   Bulk quotes on request

PRODUCT DESCRIPTION: E.coli derived recombinant.   The protein contains the VZV ORF9 immunodominant regions. Varicella-zoster virus interacts with cell surface heparin suplfate proteoglycans during virus attachment.

PURIFICATION METHOD: Purified by proprietary chromatographic technique.

PURITY: Protein is >95% pure as determined by 10% PAGE (coomassie staining).

PROTEIN CONC: 1mg/ml in 25mM Tris-Hcl pH 8.0, 1mM EDTA and 50% glycerol.

STORAGE: Protein is shipped at ambient temperature. Upon arrival, Store at -200C.

STABILITY: Five years frozen. One month in solution at room temperature.

SPECIFICITY: Immunoreactive with sera of VZV infected individuals.

APPLICATIONS: Antigen in ELISA and Western blots, excellent antigen for detection of VZV with minimal specificity problems.

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics.   It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


Recombinant Varicella Zoster Virus ORF26

Cat# RDI-VZV233-AG   $625.00/0.5mg   $1125/1mg   Bulk quotes on request

PRODUCT  DESCRIPTION: E.coli derived recombinant. The protein contains the VZV ORF26 immunodominant regions.  Varicella-zoster virus interacts with cell surface heparin suplfate proteoglycans during virus attachment.

PURIFICATION METHOD: Purified by proprietary chromatographic technique.

PURITY: Protein is >95% pure as determined by 10% PAGE (coomassie staining).

PROTEIN CONC: 1mg/ml in 25mM Tris-Hcl pH 8.0, 1mM EDTA and 50% glycerol.

STORAGE: Protein is shipped at ambient temperature. Upon arrival, Store at -200C.

STABILITY: Five years frozen. One month in solution at room temperature.

SPECIFICITY: Immunoreactive with sera of VZV infected individuals.

APPLICATIONS: Antigen in ELISA and Western blots, excellent antigen for detection of VZV with minimal specificity problems.

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics.  It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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