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ANTIBODIES  

(anti-Human and others as indicated)

RDI Division of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


dystrophic neurites surronding a senile plaque

that are histochemically stained


DATA SHEET:   Goat anti-Amyloid Precursor Protein (44-63)

Background: The amyloid precursor protein (APP) is a large membrane protein whose N terminus projects into the extracellular space. In Alzheimer's disease, this protein is broken down and releases the 42 amino acid B-amyloid protein that is found in senile plaques and vessels

Catalog#: RDI-AMYPREabG

Price: $315.00/0.25ml         $1125.00/ml 1 or more  Bulk on request


Package Size: neat serum


Species: Goat

Antigen: synthetic peptide corresponding to amino acids 44-63 of the N terminus of the human Alzheimer's Amyloid Precursor Protein (APP)

sequence: H M N V Q N G K W D D D P S G T K T C I

(control peptide available: cat#RDI-AMYPRE-CPX $470.00/1mg)


Specificity: specific for residues 44-63 on the N- terminus of APP

Optimal titers must be determined empirically by each end user.

USE: Elisa using immunizing peptide 1:1500

histochemistry (pfa fixed frozen) 1:5K

formalin fixed paraffin 1:100

(shows immunoreactivity with APP containing neurons and will label dystrophic neurites in senile plaques).

ref: Biochem Biophy Res Comm 156:432-437, 1988.

Storage: Store 4 DEG c (short term) or -20 DEG C long term. Recommend aliquot and store at -20 DEG C . Avoid frequent freeze thaw cycles.

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

Ordering terms

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