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  ANTIBODIES  

(anti-Human and others as indicated)

RDI Division of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


see below 3 polyclonals (SerpinB12, SerpinB13, SerpinB10)
Anti-SERPINB12 Polyclonal Antibody

Catalog Number: RDI-ALS24285      $312.00/100ug

                            RDI-ALS24285X   $1875.00/1mg

Lot Number:

Quantity: 100ul containing 0.02% sodium azide.

Description: Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with essential biological processes such as fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation, and apoptosis. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. However, a subset of the serpin superfamily, the ov-serpins, also resides intracellularly. A novel member of the human ov-serpin gene family, SERPINB12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestines. SERPINB12 is an inhibitor of trypsin-like serine proteinases and a new functional member of the human ov-serpin family.

Host Species: Rabbit

Specificity: Reacts with residues 260-275 of the human SERPINB12 protein.

Applications: Not tested. The investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Format: Serum

Storage: Maintain at +2-8°C for 3 months or at -20°C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.

Reference: Attardi L.D. et al. Genes Dev 2000 Mar 15;14(6):704-18.

For in vitro research use only-not for use in or on humans or animals


Anti-SERPINB13 Polyclonal Antibody

Catalog Number: RDI-ALS24286      $312.00/100ug

                            RDI-ALS24286X   $1875.00/1mg

Lot Number:

Quantity: 100ug in 100ul (1 mg/ml) in PBS containing 0.02% sodium azide.

Description: Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with essential biological processes such as fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation, and apoptosis. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. However, a subset of the serpin superfamily, the ov-serpins, also resides intracellularly. Differential display was used to identify a novel serpin (headpin or SERPINB13) that is underexpressed in squamous cell cancers of the oral cavity. SERPINB13 is expressed in normal oral mucosal tissue, skin, and cultured keratinocytes.

Host Species: Rabbit

Specificity: Reacts with residues 310-324 of the human SERPINB13 protein.

Applications: Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Format: Affinity purified IgG

Storage: Maintain at +2-8°C for 3 months or at -20°C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.

Reference: Spring P. et al. Biochem Biophys Res Commun 1999 Oct 14;264(1):299-304.

For research use only; not for use as a diagnostic.


Anti-SERPINB10 Polyclonal Antibody

Catalog Number: RDI-ALS24287       $312.00/100ug

                            RDI-ALS24287X    $1875.00/1mg

Lot Number:

Quantity: 100ul in PBS containing 0.02% sodium azide.

Description: Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with essential biological processes such as fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation, and apoptosis. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. However, a subset of the serpin superfamily, the ov-serpins, also resides intracellularly. A novel serpin gene, SERPINB10, is highly expressed in human bone marrow cells and plays a role in the regulation of protease activities during hematopoiesis.

Host Species: Rabbit

Specificity: Reacts with residues 316-330 of the human SERPINB10 protein.

Applications: Not tested. The investigator should determine the optimal dilution for a specific application.

Format: Affinity purified IgG

Storage: Maintain at +2-8°C for 3 months or at -20°C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.

Reference: Riewald M., and Schleef R.R. J Biol Chem 1995 Nov 10;270(45):26754-7.

For research use only; not for use as a diagnostic.


RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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