rev:       January 11, 2005

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  ANTIBODIES  

(anti-Human and others as indicated)

RDI Division of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


F-Box Proteins  (see 4ab below)
Anti-FBG2 (F Box 2) Polyclonal Antibody

Catalog Number:   RDI-ALS24347      $312.00/100ug

                              RDI-ALS14347X    $1875.00/1mg

Lot Number:

Quantity: 100ug in 100ul (1 mg/ml) in PBS containing 0.02% sodium azide.

Description: F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.

Host Species: Rabbit

Specificity: Reacts with residues 268-284 (SEAQPGQKHGQEEAAQS) of the human FBG2 protein.

Applications: Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Format: Affinity purified IgG

Storage: Maintain at +2-8°C for 3 months or at -20°C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.

Reference: Ilyin,G.P. et al. Gene. 2002 Aug 21;296(1-2):11-20.

For Research Use Only


Rabbit Anti-FBG3 (F Box 3) Polyclonal Antibody

Catalog Number: RDI-ALS24348         $312.00/ 100ug

                            RDI-ALS24348X      $1875.00/1mg

Lot Number:

Quantity: 100 ug in 100 ml (1 mg/ml) in PBS containing 0.02% sodium azide.

Description: F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.

Host Species: Rabbit

Specificity: Residues with residues 103-119 (EWKVEDLSRDQRKEFPN) of the human FBG3 protein. High cross reactivity: 94% identical to mouse and rat FBG3.

Applications: Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Format: Affinity purified IgG

Storage: Maintain at +2-8°C for 3 months or at -20°C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.

Reference: Ilyin,G.P. et al. Gene. 2002 Aug 21;296(1-2):11-20.

For In Vitro Research Use Only-not for use in or on humans or animals-not for use in diagnostics


Rabbit Anti-FBG4 (F Box 4) Polyclonal Antibody

Catalog Number: RDI-ALS24349      $312.00/100ug

                            RDI-ALS24349X   $1875.00/1mg

Lot Number:

Quantity: 100 ug in 100 ml (1 mg/ml) in PBS containing 0.02% sodium azide.

Description: F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.

Host Species: Rabbit

Specificity: Residues with residues 70-85 (LQLARDRSAEGRALYA) of the human FBG4 protein. Cross reacts with mouse and rat FBG4. (100% sequence identity).

Applications: Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Format: Affinity purified IgG

Storage: Maintain at +2-8°C for 3 months or at -20°C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.

Reference: Ilyin,G.P. et al. Gene. 2002 Aug 21;296(1-2):11-20.

For research use only; not for use as a diagnostic.


Anti-FBG5 (F Box 5) Polyclonal Antibody

Catalog Number: RDI-ALS24350    $312.00/100ug

                            RDI-ALS24350     $1875.00/1mg

Lot Number:

Quantity: 100ug in 100ul (1 mg/ml) in PBS containing 0.02% sodium azide.

Description: F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.

Host Species: Rabbit

Specificity: Reacts with residues 163-175 (KKQVLDLEEEGLW) of the human FBG5 protein. 76% identical to mouse.

Applications: Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Format: Affinity purified IgG

Storage: Maintain at +2-8°C for 3 months or at -20°C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.

Reference: Ilyin,G.P. et al. Gene. 2002 Aug 21;296(1-2):11-20.

For research use only; not for use in diagnostics


RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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