rev:         March 1, 2005

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  ANTIBODIES  

(anti-Human and others as indicated)

RDI Division of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


Anti-NKX3.1 Polyclonal Antibody

Catalog Number: RDI-ALS24395     $312.00/100ug

                            RDI-ALS24395X   $1875.00/1mg

Lot Number:

Quantity: 100ul or 1ml (1 mg/ml) in PBS containing 0.02% sodium azide.

Description: NKX3.1 is a homeobox gene which exhibits prostate and testis specific expression. Loss of NKX3.1 expression has been implicated in prostate development and tumorigenesis. NKX3.1 expression is dramatically down-regulated in testicular cancer of germ cell origin. Results suggest that NKX3.1 is essential for normal testis function and that its loss of expression is highly associated with the invasive phenotype of testicular germ cell tumors.

Host Species: Rabbit

Specificity: Reacts with residues 21-37 (TPSKPLTSFLIQDILRD) of human NKX3.1. This sequence is highly conserved in rat and mouse.

Applications: Western blot - Use at 1:1,000 dilution. May be diluted up to 1:5,000. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Format: Affinity purified IgG

Storage: Maintain at +2-8°C for 3 months or at -20°C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.

References: Lind G.E. et al. Mol Cancer. 2005 Feb 03;4(1):8.

                    Gelmann E.P. et al. Prostate. 2003 May 1;55(2):111-7.

For research use only; not for use in or on humans or animals-not for use in diagnostics


RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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