rev:  October 17, 2004

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Cytokines, Growth Factors & Chemokines:ANTIBODIES  

(anti-Human and others as indicated)


RDI Division of Fitzgerald Industries Intl  offers a wide line of recombinant growth factors, cytokines and chemokines and antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


SDF-1 BETA
Goat anti-human SDF-1 Beta (antigen aff pure, lyophilized, no carrier/no preservative)

cat#RDI-SDF1BabGP      $250.00/50ug

cat#RDI-SDF1BabGP1    $375.00/100ug

Goat anti-human SDF-1 Beta:Biotin conjugated (antigen aff pure, conjugated to Biotin, lyophilized, carrier free)

cat#RDI-SDF1BabGPB       $250.00/25ug

cat#RDI-SDF1BabGPB1    $375.00/50ug


Purified Rabbit Anti-Rat/Mouse SDF-1 Beta

cat# RDI-RTSDF1BabrX   $438.00

Packaging: 200ug A purified rabbit immunoglobulins, lyophilized (Reconstitute to 1 mg/ml by adding 200ul PBS; contains 0.1% sodium azide)

Immunogen: E. coli-expressed SDF-1 Beta

Reacitivty: react with rat and mouse SDF-1 Beta (other species not tested)|

Use: -1ug/ml with chemiluminescence detection Western blot detection (load 50ug whole cell lysate per lane or 1ug pure protein initially until optimized)

      -immunoprecipitation: 1:300-1:500

      -histochemistry:100+

Storage: 4°C for short term storage or -20°C in small aliquots for long term storage. Avoid repeated freeze and thaw.

Background: SDF-1b (stromal cell-derived factor-b) also known as pre-B-cell growth-stimulating factor (PBSF) is a 74-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line . Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis in mice. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin)co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry

General ref: Science 261:600-603.

                     Proc. Natl. Acad. Sci. USA 91:2305-2309.

                     Nature 328:635-638.

                    J. EXP. Med. 184:1101-1109.

                   Nature 382:829-833.

                    Nature 382:833-835.

For Research Use Only


For In Vitro Research Use Only


RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (800) 370-2222

      or (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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