rev:   November 2, 2004

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Human Cytokine/Growth Factor/Chemokines Sample Spec sheets (subject to change without notice):


DATA SHEET:  recombinant Human IP10

-IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. This recombinant human IP-10 is an 8.5 kDa protein consisting of 77 amino acids including the four conserved cysteine residues present in CXC chemokines.


Catalog#: RDI-3012

Package Size: 25 micrograms $231.00     $219.00/package 2+

                       Mini-Pack: cat#RDI-3012P $94.00/5ug        -inquire for custom sizes/bulk packaging


Supplied: Lyophilized powder with no additives.

Source: E. Coli

Purity: >98% by SDS-Page analysis . Endotoxin level is less than 0.1ng per ug of IP10.

Reconstitution: The lyophilized IP10 should be reconstituted in sterile water to a concentration of 0.1-1.0mg/ml. Allow to set at least 30 minutes at 4 DEG C , tighten cap and rotate to reconstitute any material on sides of vial. If desired, you can centrifuge at 1000 rpm for 1 minute concentrate volume in bottom of vial. This solution can be diluted into other buffered solutions or stored at 4 DEG C for up to 1 week or at -20 DEG C for future use. If this product is not being used for labelling or coating, then dilution with buffers containing at least 0.1% BSA, HSA or media is recommended.

Storage: The lyophilized powder is stable at room temperature for a few weeks but it is best stored desiccated at -20 DEG C. Reconstituted IP10 should be stored in working aliquots at -20 DEG C. AVOID FREQUENT FREEZE THAW CYCLES.

Reactivity: Determined by its ability to chemoattract human T-lymphocytes using a concentration of 10.0-50.0ng/ml.

AA Sequence:

VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE

IIATMKKKGE KRCLNPESKA IKNLLKAVSK EMSKRSP

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


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