rev:       October 19, 2004

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Human Cytokine/Growth Factor/Chemokines Sample Spec sheets (subject to change without notice):
Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


DATA SHEET:   RECOMBINANT Human Activin A

-Activin A is a TGF-beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-beta antagonist, Follistatin. This recombinant human Activin A is a 26 kDa disulfide-linked homodimer of two beta A chains, each containing 116 amino acid residues.

cat# RDI-1214     $235.00/pack    $219.00/pack 2+

Bulk or larger sizes quoted on request


Source : Insect Cells

Formulation: The sterile filtered solution was lyophilized from 50 mM Citric Acid, pH 3.0.

Purity : Greater than 95% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Reconstitution:We recommend a quick spin followed by reconstitution in water to a concentration of 50 µg/ml (e.g., 5 µg/100µl) will yield a solution of 10 mM Citric Acid, pH 3.0. This solution can then be stored at room temperature or at 4 DEG C for 1 month. It is recommended that further dilutions be made in PBS containing 2 mg/ml albumin and stored at 20 DEG C.

Stability : The lyophilized protein is stable for a few weeks at room temperature, but best stored at 20C. Reconstituted Human Activin A should be stored in working aliquots at 20 DEG C. AVOID FREQUENT FREEZE THAW CYCLES.

Biological Activity : The ED50 as detemrined by the cytolysis of murine MPC-11 cells is <2ng/ml, corresponding to a specific activity of >500K units/mg

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics.  It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


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