rev:    October 18, 2004

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Cytokines, Growth Factors & Chemokines:ANTIBODIES  

(anti-Human and others as indicated)

RDI Division of Fitzgerald Industries Intl  offers a wide line of recombinant growth factors, cytokines and chemokines and antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


IL-15 (INTERLEUKIN 15)

see below anit-human, anti-mouse and anti-rat antibodies


Rabbit anti-human IL-15(antigen aff pure, lyophilized, no carrier/no preservative)

cat#RDI-IL15abrP      $250.00/50ug

cat#RDI-IL15abrP1    $375.00/100ug

Rabbit anti-human IL-15:Biotin conjugated (antigen aff pure, conjugated toBiotin, lyophilized, carrier free)

cat#RDI-IL15abrPB      $250.00/25ug

cat#RDI-IL15abrPB1     $375.00/50ug

Mouse anti-human IL-15 500ug lyophilized

cat#RDI-IL15abmXP   $375.00  Bulk on request


Purified Rabbit Anti-mouse IL-15

cat# RDI-MIL15abr    $438.00

Packaging: 200ug Purified rabbit immunoglobulins, lyophilized (Reconstitute to 1 mg/ml by adding 200 ul PBS; contains 0.1% sodium azide)

Immunogen: E. coli-expressed mouse IL-15

Use: 0.5-1ug/ml with chemiluminescence detection Western blot detection of mouse IL-15
Cross-reactivity to IL-15 of other species has not been determined.

Storage: 4°C for short term storage or -20°C in small aliquots for long term storage. Avoid repeated freeze and thaw.

Background: IL-15 is 14-15 kDa, a member of the four alpha-helical bundle family of cytokines. It is very similar to IL-2, except that IL-15 has an IL-15 alpha receptor subunit 1. It plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules 2. This implies that IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases 3.

References:

1. Cosman, D, et al. (1995) Interleukin 15 and its receptor. Ciba Found Symp 1955:221-9

2. Waldmann, T, et al. (1998) Interleukin-2, interleukin-15 and their receptors. Int Rev Immunol 16 (3-4): 205-26

3. Kennedy, MK, et al. (1996) Characterization of interleukin-15 (IL-15) and the IL-15 receptor complex. J Clin Immunol 16 (3): 134-43

For Research Use Only

Goat anti-mouse IL-15 (in development)


Purified Rabbit Anti-RAT IL-15

cat# RDI-RTIL15Babr   $438.00

Packaging: 200ug Purified rabbit immunoglobulins, lyophilized (Reconstitute to 1 mg/ml by adding 200 ul PBS; contains 0.1% sodium azide)

Immunogen: E. coli-expressed rat IL-15 (aa 104-162)

Use: 0.5-1ug/ml with chemiluminescence detection Western blot detection of rat IL-15

Cross-reactivity to IL-15 of other species has not been determined.

Storage: 4°C for short term storage or -20°C in small aliquots for long term storage. Avoid repeated freeze and thaw.

Background: IL-15 is 14-15 kDa, a member of the four alpha-helical bundle family of cytokines. It is very similar to IL-2, except that IL-15 has an IL-15 alpha receptor subunit 1. It plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules 2. This implies that IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases 3.

References: 1. Cosman, D, et al. (1995) Interleukin 15 and its receptor. Ciba Found Symp 1955:221-9

2. Waldmann, T, et al. (1998) Interleukin-2, interleukin-15 and their receptors. Int Rev Immunol 16 (3-4): 205-26

3. Kennedy, MK, et al. (1996) Characterization of interleukin-15 (IL-15) and the IL-15 receptor complex. J Clin Immunol 16 (3): 134-43

For Research Use Only


Purified Rabbit Anti-RAT IL-15-A  (less sensitive than RDI-RTIL15Babr)

cat# RDI-RTIL15Aabr    $438.00

Packaging: 200ug Purified rabbit immunoglobulins, lyophilized (Reconstitute to 1 mg/ml by adding 200 ul PBS; contains 0.1% sodium azide


Immunogen: E. coli-expressed rat IL-15 (aa 52-103)

Use: 0.5-1ug/ml with chemiluminescence detection Western blot detection of rat IL-15
Cross-reactivity to IL-15 of other species has not been determined.


RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

Ordering terms

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